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Research to Prevent Blindness

Grants Database

Research to Prevent Blindness (RPB) provides grants to high-performing U.S.-based departments of ophthalmology and to their high-potential investigators. Use our Grants Database to learn more. Award amounts for some grants are distributed over multiple years.

How to use the Grants Database

Refine your search by using the filter at left. Search by setting a date range, or filter your results by institution, research area keyword, or awardee.  Sort the table by clicking on any column header.  

Learn about an institution or individual by clicking on a name.

Learn about RPB-supported work by clicking on the text link "Research funded by this award," which will take you to our Research Database where you can refine and/or expand a search for published studies. (Note: In some cases this link will not be available because a researcher may have only recently received an award and has yet to publish findings.)

RPB Grant Awards from 2023 & 2024

67 Awards ($13,978,350)

RPB Grant Type
Year
Award
Research Area
Awardee
Institution
Career Advancement Award 2024 $150,000 Glaucoma Herberg, Samuel / PhD State University of New York Upstate Medical University
Will investigate whether targeting epigenetics (cellular processes that regulate gene activity without altering the DNA sequence) has the potential to improve glaucomatous outflow tissue defects in high-pressure glaucoma, a blinding disease.
Career Advancement Award 2024 $150,000 Visual Neuroscience Sinha, Raunak / PhD University of Wisconsin-Madison School of Medicine & Public Health
Will increase our fundamental understanding of the functional maturation of the fovea (the area of the retina that provides high-resolution daylight vision via cone photoreceptors)—currently poorly understood in terms of how the fovea re-organizes and develops after birth.
Career Advancement Award 2024 $150,000 Glaucoma Xu, Benjamin / MD, PhD Keck School of Medicine of the University of Southern California
Will demonstrate the feasibility of an AI-enhanced tele-glaucoma program for providing timely access to reproducible, equitable and resource-efficient glaucoma care.
Career Development Award 2024 $350,000 Glaucoma Aboobakar, Inas F. / MD Harvard Medical School
Because several genes associated with glaucoma risk have roles in the mitochondria, the energy-producing part of our cells, the researcher will use cutting-edge genetic technologies to measure the quantity and quality of DNA found in the mitochondria in people with and without glaucoma.
Career Development Award 2024 $350,000 Biochemistry, Molecular Biology, Retina, Retinal Cell Biology Miller, Jason Matthew Lewis / MD, PhD The Regents of the University of Michigan School of Medicine
Will explore the potential ability of an organelle called peroxisome to degrade the lipid-rich deposits that occur in people with AMD when mitochondria, which typically get rid of this build-up, are not functioning properly due to the disease.
Career Development Award 2024 $350,000 Retinal Cell Biology Todd, Levi / PhD State University of New York Upstate Medical University
Building on his previous research, the candidate will answer critical questions about the potential for mammals to regenerate the retina using Muller glia, a support cell in the retina, as a source of neuronal replacement.
Career Development Award 2024 $350,000 Retina Vlasits, Anna Louise / PhD University of Illinois Chicago College of Medicine
Will study Fragile X syndrome, a neurodevelopmental disorder that causes learning disabilities, autism and visual symptoms (including reduced contrast sensitivity), to determine whether symptoms are caused by changes in the retina or the brain.
Catalyst Award for Innovative Research Approaches for Age-Related Macular Degeneration 2024 $300,000 Retina Dunaief, Joshua L / MD, PhD University of Pennsylvania School of Medicine
Will explore the role of bile acids, if any, in AMD pathogenesis and develop drug or gene therapies to augment the levels of helpful bile acids.
Catalyst Award for Innovative Research Approaches for Age-Related Macular Degeneration 2024 $300,000 Biochemistry, Molecular Biology, Pharmacology, Physiology, Retina, Retinal Cell Biology Palczewski, Krzysztof / PhD University of California, Irvine, School of Medicine
Will develop innovative approaches aimed at regulating vascular endothelial growth factor (VEGF-A), which promotes blood vessel growth, through the introduction of highly specific proteases in botulinum neurotoxin (commonly known as Botox) that target VEGF-A.
Catalyst Award for Innovative Research Approaches for Age-Related Macular Degeneration 2024 $300,000 Retina Sepah, Yasir / MBBS Stanford University School of Medicine
Will develop a more precise and personalized method for detecting and monitoring retinal diseases like geographic atrophy and Stargardt disease by integrating advanced imaging techniques with functional testing (adaptive optics imaging with image-guided microperimetry)
Stein Innovation Award 2024 $300,000 Amblyopia, Eye Movements, Neuro-Ophthalmology, Strabismus Feinberg, Evan / PhD University of California, San Francisco, School of Medicine
Will test the hypothesis that strabismus (misalignment of the eyes) originates in a specific area of the brain that functions as a hub for shaping several different eye movements.
Stein Innovation Award 2024 $300,000 Biochemistry, Cell Biology, Development, Immunology, Microbiology, Molecular Biology, Retina, Retinal Cell Biology Giger, Roman J. / PhD The Regents of the University of Michigan School of Medicine
Will explore ways to alter the retinal environment to promote retinal repair (following visual system trauma or in relation to eye transplantation), which is currently hampered by the body’s own immune system, which can damage newly forming blood vessels.
Career Development Award 2024 $350,000 Retinal Cell Biology Pfeiffer, Rebecca Lynne / PhD University of Utah Health Sciences Center
Will advance our understanding of the connectivity of Muller cells (cells in the inner retina that have important roles in synaptic modulation, preservation, and metabolic support), which is largely unknown, and will provide the groundwork for understanding how these connections change with disease.
Career Development Award 2024 $350,000 Retina Rossin, Elizabeth J. / MD, PhD Harvard Medical School
Will expand the known genetic underpinnings of central serous chorioretinopathy (CSCR), an inherited vision-threatening maculopathy seen commonly by retina specialists, to understand how they affect choroidal anatomy and serum proteins in patients.
Career Development Award 2024 $350,000 Immunology, Microbiology Walsh, James / MD, PhD Washington University in Saint Louis School of Medicine
Will explore the role of the choroid, a vascular layer that sits outside of the blood-retina barrier, as an immunologically active area within the eye that may play a critical role in autoimmune uveitis, which is an inflammatory disease of the eye’s uvea.
Disney Award for Amblyopia Research 2024 $150,000 Amblyopia, Eye Movement Disorders, Neuro-Ophthalmology, Strabismus Triplett, Jason / PhD Children's National Hospital
Will study the molecular- and activity-dependent mechanisms underlying functional changes in the superior colliculus (a midbrain nucleus that integrates multisensory inputs to regulate head and eye movements) in amblyopia, which are currently completely unknown.
Low Vision Research Award 2024 $300,000 Retina, Visual Neuroscience, Visual Psychophysics Dunn, Felice Audris / PhD University of California, San Francisco, School of Medicine
Will develop more scalable, sensitive diagnostic methods for the clinical measurement of graded photoreceptor loss.
Medical Student Eye Research Fellowship 2024 $30,000 Clinical, Epidemiologic, Glaucoma, Retina Chen, Xindi Johns Hopkins University School of Medicine
Conducting research at The Johns Hopkins University School of Medicine.
Medical Student Eye Research Fellowship 2024 $30,000 Retina Coral Du, Katherine University of Pittsburgh School of Medicine
Conducting research at the University of Pittsburgh School of Medicine.
Medical Student Eye Research Fellowship 2024 $30,000 Retina, Retinal Cell Biology Cuamatzi Castelan, Andrea S. Northwestern University Feinberg School of Medicine
Conducting research at Northwestern University Feinberg School of Medicine.
Medical Student Eye Research Fellowship 2024 $38,000 Amblyopia, Eye Movement Disorders, Neuro-Ophthalmology, Strabismus, Visual Neuroscience Householder, Nicholas A. Keck School of Medicine of the University of Southern California
Conducting research at Keck School of Medicine of the University of Southern California.

*Recipient of an additional $8,000 relocation stipend.
Medical Student Eye Research Fellowship 2024 $38,000 Retina Sutter, David Oregon Health & Science University School of Medicine
Conducting research at Oregon Health & Science University.

*Recipient of an additional $8,000 relocation stipend.
RPB International Research Collaborators Award 2024 $75,000 Amblyopia, Eye Movement Disorders, Neuro-Ophthalmology, Strabismus Ghasia, Fatema / MD Cleveland Clinic Lerner College of Medicine of CWRU
Will revolutionize amblyopia care by creating an innovative AI-based approach to diagnose and assess the treatment of amblyopia, a leading cause of preventable blindness.
Special Grant 2024 $280,000 American Academy of Ophthalmology
Award given in partnership with the American Academy of Ophthalmology (AAO). Designed to enable researchers to use AAO’s IRIS Registry—the nation’s first and largest comprehensive eye disease clinical registry—to conduct population-based studies in ophthalmology and blindness prevention.
Special Grant 2024 $125,000 Association of University Professors of Ophthalmology
AUPO is a key ally in RPB's commitment to enrich the development of the Chairs, Directors of Research, and other leaders from departments of ophthalmology.
Stein Innovation Award 2024 $300,000 Retina Jones, Bryan William / PhD University of Utah Health Sciences Center
Will study the retinas of ground squirrels, which, during hibernation, degenerate their photoreceptors, then disassemble the synapses connecting photoreceptors from the rest of the retina. When these synapses disassemble, they look like synapses in human retinal degenerative disease such as retinitis pigmentosa or age-related macular degeneration. However, when ground squirrels emerge from hibernation, they regenerate photoreceptors and reconnect synapses.
Stein Innovation Award 2024 $300,000 Visual Neuroscience Schwartz, Gregory W. / PhD Northwestern University Feinberg School of Medicine
Will create a new way to measure dysfunction in retinal ganglion cells (RGCs), which transmit signals that are essential for vision to the brain, by tracking RGC light responses (or “spikes”), rather than cell survival, as the primary outcome measure.
Stein Innovation Award 2024 $300,000 Retina Sparrow, Janet R. / PhD Columbia University Irving Medical Center
Patients with retinitis pigmentosa (RP), a hereditary retinal disorder that causes progressive vision loss, often present with an aberrant pattern of increased brightness in images of blue fundus autofluorescence. The researcher will use a mouse model to determine whether the increased production of toxic molecules (bisretinoid lipofuscin), that are the source of the increased autofluorescence, contribute to disease progression in RP.
Stein Innovation Award 2024 $300,000 Physiological Optics, Retina, Visual Psychophysics Srinivasan, Vivek / PhD New York University Grossman School of Medicine
Will utilize a state-of-the-art imaging technology to measure more precisely the rod system (the photoreceptors lining the back of the eye, which are responsible for vision in low light), to identify markers for age-related macular degeneration (AMD) progression.
Stein Innovation Award 2024 $300,000 Biochemistry, Cell Biology, Genetics, Glaucoma, Molecular Biology, Systems Biology Zode, Gulab / PhD University of California, Irvine, School of Medicine
Will utilize cutting-edge techniques to deliver gene editing to the trabecular meshwork (TM), a tissue in the eye that can be damaged by mutant myocilin, leading to high intraocular pressure and a severe form of glaucoma.
Career Advancement Award 2023 $150,000 Anatomy, Glaucoma, Ocular Oncology, Pathology Huang, Alex A. / MD, PhD University of California, San Diego, School of Medicine
Will uncover the molecular pathways that are activated after glaucoma filtration surgeries and cause surgical failure, with the ultimate aim of improving glaucoma treatments.
Career Advancement Award 2023 $150,000 Pharmacology, Physiology Kiser, Philip D. / PharmD, PhD University of California, Irvine, School of Medicine
Will study the role of cellular retinaldehyde-binding protein in the metabolic pathways known as visual cycles, which generate the key light-sensitive molecule of the retina.
Career Advancement Award 2023 $150,000 Glaucoma Segre, Ayellet V. / MSc, PhD Harvard Medical School
Will integrate cell type-specific genetic regulation in the outflow pathway, retina and optic nerve head with genetic associations to uncover causal mechanisms for primary open-angle glaucoma.
Career Development Award 2023 $350,000 Retinal Cell Biology Amamoto, Ryoji / PhD Harvard Medical School
Will promote cone photoreceptor survival in Retinitis Pigmentosa (RP) in order to prolong daylight color vision for all patients suffering from RP, which is caused by more than 65 different genes.
Career Development Award 2023 $350,000 Glaucoma Liu, Katy / MD, PhD Duke University School of Medicine
Will identify and characterize the genetic signatures of immune cells that regulate intraocular pressure to uncover how immune cells affect intraocular pressure in the healthy state and in glaucoma.
Career Development Award 2023 $350,000 Amblyopia, Clinical, Epidemiologic, Eye Movement Disorders, Neuro-Ophthalmology, Strabismus Oke, Isdin / MD, MPH Harvard Medical School
Will address delayed diagnosis of amblyopia, the most common cause of vision loss in children in the US, through machine learning using data from the American Academy of Ophthalmology’s IRIS® Registry.
Career Development Award 2023 $350,000 Clinical, Cornea, Epidemiologic Redd, Travis K / MD, MPH Oregon Health & Science University School of Medicine
Will develop and evaluate artificial intelligence systems to automatically determine the underlying cause of infectious keratitis (or “corneal ulcer”), a major cause of blindness worldwide, using smartphone photographs and clinical history data.
Catalyst Award for Innovative Research Approaches for Age-Related Macular Degeneration 2023 $300,000 Retinal Cell Biology Apte, Rajendra S. / MD, PhD Washington University in Saint Louis School of Medicine
Will explore how impaired lipid transport and removal from the eye cause lipid-rich deposits (drusen) to develop in the eye in AMD.
Catalyst Award for Innovative Research Approaches for Age-Related Macular Degeneration 2023 $300,000 Biochemistry, Molecular Biology, Retina Mahajan, Vinit / MD, PhD Board of Trustees of the Leland Stanford Junior University
Will establish a high-resolution proteomic platform using human AMD aqueous humor biopsies, which exhibit high accessibility and minimal invasiveness compared to vitreous biopsies.
Catalyst Award for Innovative Research Approaches for Age-Related Macular Degeneration 2023 $300,000 Retina, Retinal Cell Biology Rao, Rajesh C. / MD The Regents of the University of Michigan School of Medicine
Will explore a non-coding genetic variant, which increases the risk—via unknown mechanisms—for Dry and Wet AMD by ~10-fold, and its potential effects on the expression of other genes.
Medical Student Eye Research Fellowship 2023 $38,000 Anatomy, Ocular Oncology, Pathology Alvarez, Osmel P. University of Miami Miller School of Medicine
Conducting research at the University of Miami Miller School of Medicine.

*Recipient of an additional $8,000 relocation stipend.
Medical Student Eye Research Fellowship 2023 $30,000 Biochemistry, Clinical, Epidemiologic, Molecular Biology, Retina, Retinal Cell Biology Gomes, Isabella Washington University in Saint Louis School of Medicine
Conducting research at Washington University in St. Louis School of Medicine.
Medical Student Eye Research Fellowship 2023 $38,000 Retina Jo, Jason (Jace) University of Wisconsin-Madison School of Medicine & Public Health
Conducting research at the University of Wisconsin-Madison School of Medicine & Public Health.

*Recipient of an additional $8,000 relocation stipend.
Medical Student Eye Research Fellowship 2023 $30,000 Glaucoma Keehn, Caroline Baylor College of Medicine
Conducting research at Baylor College of Medicine.
Medical Student Eye Research Fellowship 2023 $38,000 Immunology, Microbiology Onyekwere, Oluomachi Board of Trustees of the Leland Stanford Junior University
Conducting research at the Board of Trustees of the Leland Stanford Junior University.

*Recipient of an additional $8,000 relocation stipend.
Medical Student Eye Research Fellowship 2023 $30,000 Retinal Cell Biology Shah, Madhura Harvard Medical School
Conducting research at Harvard Medical School / SERI.
Medical Student Eye Research Fellowship 2023 $38,000 Cornea Zhang, Lyvia J. Harvard Medical School
Conducting research at Harvard Medical School / MEEI.

*Recipient of an additional $8,000 relocation stipend.
Physician-Scientist Award 2023 $300,000 Clinical, Epidemiologic VanderBeek, Brian L. / MD, MPH, MSCE University of Pennsylvania School of Medicine
Will create accurate, current national prevalence and incidence measurements of diabetic retinal disease (DRD).
Physician-Scientist Award 2023 $300,000 Cornea Yin, Jia / MD, PhD, MPH Harvard Medical School
Will explore the direct relationship between blood vessels and corneal sensory nerves, which is of high relevance in ocular tissues.
RPB International Research Collaborators Award 2023 $75,000 Retina Tabin, Geoffrey / MD Board of Trustees of the Leland Stanford Junior University
Will establish a school-screening program for retinal disease among adolescents in Ghana, where patients with Type 1 diabetes (T1D) and sickle cell disease (SCD) have high rates of potentially blinding retinopathy.
RPB International Research Collaborators Award 2023 $75,000 Low Vision Xiong, Yingzi / PhD Johns Hopkins University School of Medicine
Will create a standardized Orientation and Mobility (O&M) assessment tool for the large population of adults with low vision that is patient-centered, scientifically supported, and takes comorbidities into consideration.
Stein Innovation Award 2023 $300,000 Genetics, Systems Biology Kay, Jeremy N. / PhD Duke University School of Medicine
Will build an encyclopedia of retinal disease gene isoforms and their expression sites in mouse and human retina in order to provide transformative insights into pathophysiology of many inherited retinal disease (IRD)-associated genes.
Stein Innovation Award 2023 $300,000 Genetics, Systems Biology Moraes, Carlos T. / PhD University of Miami Miller School of Medicine
Will employ novel synthetic biology tools to create models and treatments for mitochondrial ophthalmological diseases.
Career Development Award 2023 $350,000 Immunology, Microbiology, Retina, Retinal Cell Biology Maidana, Daniel E. / MD, PhD University of Illinois Chicago College of Medicine
Will test the hypothesis that microglia reduce photoreceptor (light sensing) cell death in acute retinal detachment and increase photoreceptor cell death in chronic retinal detachment.
Career Development Award 2023 $350,000 Retinal Cell Biology Spencer, William J. / PhD State University of New York Upstate Medical University
Will conduct a study to understand the mechanistic basis for disc (light-sensitive membrane) formation in healthy photoreceptors (light sensing cells) and determine if reducing the abnormal release of vesicles in diseased retinas could have therapeutic value.
Career Development Award 2023 $350,000 Retina Toomey, Christopher B. / MD, PhD University of California, San Diego, School of Medicine
Will study the formation of drusen (lipoprotein-rich deposits), the primary lesions of age-related macular degeneration (AMD) that occur in early stages of the disease, before vision loss is detected.
Career Development Award 2023 $350 Retina, Retinal Cell Biology Yoshimatsu, Takeshi / PhD Washington University in Saint Louis School of Medicine
Will establish zebrafish as a model system of human macula diseases such as age-related macular degeneration (AMD), building on the recent finding that zebrafish feature a macula-like specialization in the eye.
Disney Award for Amblyopia Research 2023 $100,000 Visual Neuroscience Fong, Ming-fai / PhD Georgia Tech Research Corporation
Will conduct studies to determine whether suppressing activity in a subset of retinal cells is sufficient to promote recovery from amblyopia.
Low Vision Research Award 2023 $300,000 Neuro-Ophthalmology, Visual Psychophysics Diaz, Gabriel J. / PhD The Rochester Institute of Technology
Will study the impact of cortical blindness (CB), which includes hemianopia and quadrantanopia, on driving behavior (specifically steering) with a novel virtual reality steering task developed for this study.
Low Vision Research Award 2023 $300,000 Amblyopia, Eye Movement Disorders, Neuro-Ophthalmology, Strabismus Liao, Yaping Joyce / MD, PhD Board of Trustees of the Leland Stanford Junior University
Will take the initial steps to develop the first artificial intelligence platform for fast, real-time diagnosis of visual impairment based on oculomotor recordings, which are shown to be predictive of disease.
Medical Student Eye Research Fellowship 2023 $30,000 Anatomy, Cornea, Ocular Oncology, Pathology Greenfield, Jason A. University of Miami Miller School of Medicine
Conducting research at the University of Miami Miller School of Medicine.
Medical Student Eye Research Fellowship 2023 $30,000 Clinical, Epidemiologic Murillo, Karla University of California, Los Angeles
Conducting research at The Regents of the University of California, Los Angeles.
Medical Student Eye Research Fellowship 2023 $30,000 Clinical, Epidemiologic Radgoudarzi, Niloofar University of California, San Diego, School of Medicine
Conducting research at the University of California, San Diego, School of Medicine.
RPB International Research Collaborators Award 2023 $75,000 Immunology, Microbiology Bispo, Paulo J.M. / MS, PhD Harvard Medical School
Will explore solutions to overcome the growing threat of antibiotic-resistant bacteria in ophthalmology using bacteriophages (or phages), which are viruses that infect bacteria and can disrupt the bacterial cells.
Special Grant 2023 $125,000 Association of University Professors of Ophthalmology
AUPO is a key ally in RPB's commitment to enrich the development of the Chairs, Directors of Research, and other leaders from departments of ophthalmology.
Stein Innovation Award 2023 $300,000 Biochemistry, Molecular Biology, Retinal Cell Biology Handa, James T. / MD Johns Hopkins University School of Medicine
Will elucidate how photoreceptors (light sensing cells) and the retinal pigment epithelium (RPE), which are key cells that protect photoreceptors, can communicate in health and under stress through the exchange of genetic material, shedding light on potential new treatments for early AMD.
Stein Innovation Award 2023 $300,000 Glaucoma Hu, Yang / MD, PhD Board of Trustees of the Leland Stanford Junior University
Will identify the most suitable gene therapy vectors to create neuroprotective treatments for glaucoma, the most common cause of irreversible blindness.

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